Recombinant Mouse GM-CSF Protein (14.2 kDa)

IBI’s recombinant mouse GM-CSF protein is a high-quality, bioactive protein designed for advanced research applications. Produced using a Pichia pastoris (yeast) system, this protein benefits from natural folding and post-translational modifications, ensuring superior functionality and greater resemblance to its native form compared to E. coli systems. Free from endotoxins, HIS-TAGS, and carriers, this protein has a predicted molecular weight of 14.2 kDa, making it ideal for reliable experimental outcomes.

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a critical cytokine secreted by macrophages, T cells, NK cells, endothelial cells, and fibroblasts in response to inflammatory stimuli such as LPS, IL-1, and TNF-α. It plays a vital role in immune regulation by stimulating stem cells to produce granulocytes and monocytes. GM-CSF also promotes cellular responses to inflammation and is glycosylated in its mature form. The biological activity of IBI’s GM-CSF protein has been verified through cell proliferation assays using the FDC-P1 cell line, with an ED50 of 0.0015 - 0.0023 ng/mL.

Shipped lyophilized at room temperature without carrier protein, IBI’s recombinant mouse GM-CSF protein can be reconstituted in sterile PBS with a carrier such as BSA or cell assay media. It is suitable for applications in cell culture, as a GM-CSF ELISA standard, or as a Western Blot control, offering precision and reliability for immunology and inflammation research.

 All IBI recombinant proteins are lyophilized and shipped at room temperature without carrier protein and can be reconstituted in sterile PBS with at least 0.1% carrier protein, such as BSA or cell assay media. The GM-CSF mouse protein is suitable for use in cell culture, as a GM-CSF ELISA Standard, and as a Western Blot Control. Country of Origin: USA.