Recombinant Mouse TNF Alpha Protein (17.3 kDa)

IBI’s recombinant mouse TNF alpha protein offers unparalleled quality and performance for your research needs. Produced in a Pichia pastoris (yeast) expression system, this protein benefits from superior folding and post-translational modifications, ensuring enhanced bioactivity compared to those expressed in E. coli systems. Free of endotoxins, HIS-TAGS, and carriers, it is naturally folded and mimics its host form with remarkable fidelity. With a predicted molecular weight of 17.3 kDa, this recombinant protein provides consistency and reliability for diverse applications.

 

TNF alpha, a critical member of the TNF Superfamily, is known for its pivotal role in regulating immune responses. It is chiefly produced by activated macrophages, alongside various other cell types such as lymphoid cells, mast cells, and fibroblasts. This endogenous pyrogen is involved in key biological processes, including fever induction, apoptosis, inflammation, and the inhibition of tumorigenesis. Shipped lyophilized at room temperature without carrier protein, IBI’s TNF alpha mouse protein is ideal for cell culture, use as an ELISA standard, or as a Western Blot control.